Bi
341 Genetics
Dr. David Oline
Dept. of Biology
Southern
Class begins
Monday, Sept. 29
10:00 am in
Sciences 108
Please check
the bookstore for your lab manuals
The first week
of lab is a field trip – rain or shine!
Course
Schedule (See below for updated schedule and
assignments)
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As of 10/1/08, the
count was 755
complete microbial genomes 23
complete eukaryotic genomes |
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Week 1
M Introduction
Problems: Chpt. 1 1,
4, 7, 6, 9
Add
the terms “allele” and “dominant” to the concept map on p. 21
In class materials
(slides/overheads)
$3 billion for
studying bear DNA
W DNA
structure
Problems: Chpt. 2 7,
9, 11, 12, 14, 18, 19, 25
In class materials
(overheads)
Overview of the red fir
project
F Gene
and Genome structure
Problems: Chpt.
2 22, 25, 34
In class materials
(overheads/slides)
Week 2
M Gene
Function
In class materials
(overheads)
ANSWERS TO CHAPTER 1 and 2 PROBLEMS
W QUIZ!!
Gene Function
Problems: Chpt. 3 2,
5, 7, 11, 14, 19, 21, 24 (null allele means a mutation that causes a loss of
function of that protein in the phenotype)
F Gene
Function cont.
RNA
The Central
Dogma
2008
Nobel Prize for Green Fluorescent Protein
Week
3
Gene Function cont.
Transcription
and Translation
In-class materials
(overheads)
Really Cool Transcription and Translation
Animation
W QUIZ! The quiz
covers only chapter 3, but all of our readings from chapter 3! Emphasis will be on lecture.
Don’t forget the lab questions, though.
F
DNA replication
Problems: Chpt. 4 1,
4, 5, 6, 15, and go through solved problem #2 on p114
Realistic DNA Replication Animation
In-class materials
(slides/overheads)
Week
4
M Mendelian
Genetics / Crosses
Problems: Chpt. 5 2,
3, 4, 5, 7, 8, 9
In-class materials
(overheads)
ANSWERS TO
CHAPTERS 4 AND 5 PROBLEMS
W QUIZ!!
Mendelian Genetics /
Pedigrees
Problems: Chpt. 5 10,
11, 13, 16, 21
In-class materials
(overheads)
F Mendelian
Genetics / Pedigrees
Gel
Electrophoresis Animation I
Gel
Electrophoresis Animation II
Week
5
M Recombination
Problems: Chpt. 6 4,
5, 7, 12, 24
In-class materials
(overheads/slides)
ANSWERS TO CHAPTERS 5 AND 6 PROBLEMS
W QUIZ!!
Recombination
F Genetic
Engineering / Cloning
Readings Chpt. 8 p214-226
Problems Chpt. 8 1, 2, 4, 6, 7
Week 6
M LAB
ASSIGNMENT #1 DUE
Genetic
Engineering / Cloning
Readings Chpt. 8 p226-p232, Figures 8-18 and 8-20
p236-239
Problems Genetic Engineering
Problems Handout
Really Cool
Life-like Plasmid Cloning Animation
In-class materials
(slides/overheads)
W QUIZ
MOVED TO FRIDAY!!
Lab this week – we will
START only the PLASMID MAPPING LAB – and we will work on problems
Genetic Engineering /
Libraries, DNA Sequencing
Creating
a genomic DNA library
In-class materials
(overheads)
Lab Problems
Worksheet Answers
Chapter 8 and Genetic
Engineering Problems Answers
F QUIZ!!
– A Take-Home Due on Monday
Genetic
Engineering / Libraries, DNA Sequencing
Screening
Plasmids using Xgal Animation
In-class materials
(overheads)
Examples of Good Student
Papers from Previous Years: Paper 1, Paper 2, Paper 3
*Please note that I
limited them to 2 pages or less, so these are very compressed – I have not
limited you to 2 pages.
Week
7
M DRAFT
OF RED FIR PAPER DUE – ANYTIME BY THE END OF THE DAY
TAKE-HOME
QUIZ DUE – IN CLASS 10:00 AM!!
Capillary DNA
Sequencing Animation
In-class materials
(overheads/slides)
DNA Sequencing/Genomics
Readings: Chapter 9 p288-303
Problems: Chapter 8 16
Chapter 9 7, 9, 10, 13
W Lab
this week – we will FINISH the PLASMID MAPPING LAB and work on problems
Lab Assignment #2 will
be handed out
Genomics
DNA Sequencing/Genomics
Readings: Chapter 9 p288-305
Problems: Chapter 8 16
Chapter 9 7, 9, 10, 13
In-class materials
(overheads/slides)
F QUIZ!!
Mutation
Readings: Chapter 10 p315-319, p324 (Ames test)
Problems: Chapter 10 1, 2, 8, 12, 13
In-class materials
(overheads/slides)
Week 8
M Lab
Assignment #2 DUE
Mutation
Readings: Chapter 10 p315-319, p324 (Ames test)
Problems: Chapter 10 1, 2, 8, 12, 13
In-class materials
(overheads/slides)
RED FIR
PAPER COMMON COMMENT DOS AND DON’TS
W Chromosomal Mutations
Readings: Chapter 11 p351-355, p358-363
Problems: Chapter 11 11, 13, 14, 17
In-class materials
(overheads/slides)
ANSWERS TO CHAPTERS
10 AND 11 PROBLEMS
WEDNESDAY LAB MEET IN THE LIBRARY
ELECTRONIC CLASSROOM 114 AT 3:00 PM!!
THURSDAY AM LAB MEET IN
TAYLOR 203 AT 9:00 AM
THURSDAY PM LAB MEET IN
TAYLOR 203 AT 2:00 PM
F IN-CLASS
QUIZ!! Chapters 10 and 11 ONLY!
Readings: Chapter 13 p420-432 (lac operon)
Problems: Chapter 13 go through solved problesm 1, 2, 3, and 4
Chapter
13 1, 2, 3, 5, 6
The
Lac Operon – induction by lactose
TAKE
HOME QUIZ COVERING MENDELIAN GENETICS, CHI-SQ, AND RECOMBINATION HANDED OUT!
Click here for the
compiled Monkey Data worksheet from the Bioinformatics Lab
IF YOU FORGOT TO PICK
ONE UP IN CLASS TODAY, HERE IS THE TAKE-HOME DUE ON MONDAY
Week
9
M Readings:
Chapter 13 p420-432 (lac operon)
Problems: Chapter 13 go through solved problesm 1, 2, 3, and 4
Chapter
13 1, 2, 3, 5, 6
TAKE
HOME QUIZ COVERING MENDELIAN GENETICS, CHI-SQ, AND RECOMBINATION DUE!
The
Lac Operon – induction by lactose
In-class materials
(overheads/slides)
W BIOINFORMATICS REPORT DUE!
Population Genetics
Readings: Chapter 17 p554-575
Problems: Chapter 17 1, 2, 3, 4, 5,
In-class materials
(overheads/slides)
F THANKSGIVING!!
Week
10
M Population
Genetics
Readings: Chapter 17 p554-575
Problems: Chapter 17 1, 2, 3, 4, 5,
Problem
Sheet Handout
Population Genetics
Problems Handout
In-class materials
(overheads/slides)
W
Population Genetics
Readings: Chapter 17 p554-575
Problems: Chapter 17 1, 2, 3, 4, 5,
Problem
Sheet Handout
F FINAL
DRAFTS OF RED FIR PAPER DUE!!
Population
Genetics
By way of review, let’s
do some integrative problems in class!
FINALS WEEK
M 7:30 AM!!!! FINAL EXAM