This podium presentation's purpose is to help others understand as to why the protein dystrophin is so important in our muscle cells and why dystrophin deficient muscle cells cause Duchenne Muscular Dystrophy. This includes not only a description of Duchenne Muscular Dystrophy, but also an analysis of muscle contraction, the structure of dystrophin and the dystrophin-glycoprotein complex. By understanding these three points and looking at the different types of mutations that cause Duchenne Muscular Dystrophy, one can understand why this fatal disease occurs.