This study gave students practical experience with cyberspace communication in dealing with medical issues. The design of the exploratory study is qualitative, using open-ended questionnaires, interviews, and group discussions. The sample was drawn from a senior 400-level seminar for both nursing and marketing students. Analysis within and between interviews explored communication barriers and strategies for exploring topics and completing written and oral presentations, including practical hands-on experience using innovative new millennium communication methods and channels for research and clinical issues in doctor-patient consultations, examinations, robotic medicine, personalized medicine, etc. Topics included Internet implications for information access; digital medical records; privacy issues; digital prescriptions; on-line pharmacies; and centralizing or deregulating public health care systems. Communication models included on-line forums, chat rooms, Skype, remote meetings, Google Docs, and relationship and “friend” specific communication on Facebook, Twitter, Ning, and Linked-in, including the role of wealth and resources and international comparisons.